Drug Delivery: Enzyme‐Responsive Release of Doxorubicin from Monodisperse Dipeptide‐Based Nanocarriers for Highly Efficient Cancer Treatment In Vitro (Adv. Funct. Mater. 8/2015) | Zendy

Zhang He | Zendy; Fei Jinbo | Zendy; Yan Xuehai | Zendy; Wang Anhe | Zendy; Li Junbai | Zendy

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Drug Delivery: Enzyme‐Responsive Release of Doxorubicin from Monodisperse Dipeptide‐Based Nanocarriers for Highly Efficient Cancer Treatment In Vitro (Adv. Funct. Mater. 8/2015)

Author(s) -

Zhang He,

Fei Jinbo,

Yan Xuehai,

Wang Anhe,

Li Junbai

Publication year - 2015

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201570057

Subject(s) - nanocarriers , materials science , drug delivery , doxorubicin , nanotechnology , drug , glutaraldehyde , nanoparticle , targeted drug delivery , pharmacology , chemistry , organic chemistry , medicine , chemotherapy , surgery

Cationic diphenylalanine can self‐assemble into biocompatible and biodegradable nanoparticles through cross‐linkage of glutaraldehyde. As shown by X. Yan, J. Li, and colleagues on page 1193, such assembled nanoparticles have a typical enzyme‐responsive characterization and can be employed as nanocarriers for drug delivery. The doxorubicin‐loaded nanocarriers with a lower drug concentration still possess a higher efficiency in killing cancer cells.

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