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Photodynamic Therapy: Highly Biocompatible Carbon Nanodots for Simultaneous Bioimaging and Targeted Photodynamic Therapy In Vitro and In Vivo (Adv. Funct. Mater. 37/2014)
Author(s) -
Choi Yuri,
Kim Seongchan,
Choi MyungHo,
Ryoo SooRyoon,
Park Jongnam,
Min DalHee,
Kim ByeongSu
Publication year - 2014
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201470245
Subject(s) - photodynamic therapy , materials science , photosensitizer , in vivo , nanodot , biocompatible material , conjugated system , nanotechnology , photochemistry , biomedical engineering , medicine , chemistry , organic chemistry , microbiology and biotechnology , composite material , polymer , biology
On page 5781, targeted delivery of photosensitizer (PS) and therapeutic photodynamic effect are achieved by folic acid (FA) conjugated carbon dot (CD) as a carrier of PS, zinc phthalocyanine (ZnPc). D.‐H. Min, B.‐S. Kim and colleagues demonstrate how the CDs prepared by thermal decomposition of α‐cyclodextrin are biocompatible, highly fluorescent, and water dispersible. The ZnPc‐loaded FA‐conjugated CD shows excellent efficacy as photodynamic therapy to the target cancer cells upon irradiation.