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Cancer Treatment: Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser (Adv. Funct. Mater. 27/2014)
Author(s) -
Wang Liming,
Lin Xiaoying,
Wang Jing,
Hu Zhijian,
Ji Yinglu,
Hou Shuai,
Zhao Yuliang,
Wu Xiaochun,
Chen Chunying
Publication year - 2014
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201470174
Subject(s) - photothermal therapy , materials science , nanocarriers , nanotechnology , photothermal effect , plasmon , cancer cell , cancer , cancer research , drug delivery , optoelectronics , medicine
On page 4229, X. Wu, C. Chen, and co‐workers discuss a simple strategy to combat cancer drug resistance using plasmonic‐based photothermal properties. A localized mild photothermal stimulus can modulate the drug‐resistance‐related genes and thus enhance drug sensitivity and accumulation in resistant breast cancer cells. The integrated nanoplatform combining photothermal therapy with chemotherapy promises to inhibit a wide range of resistances.