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Back to Basics: Exploiting the Innate Physico‐chemical Characteristics of Nanomaterials for Biomedical Applications
Author(s) -
Tay Chor Yong,
Setyawati Magdiel Inggrid,
Xie Jianping,
Parak Wolfgang J.,
Leong David Tai
Publication year - 2014
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201401664
Subject(s) - nanomedicine , unintended consequences , nanotechnology , nanomaterials , materials science , risk analysis (engineering) , biochemical engineering , business , engineering , nanoparticle , political science , law
In nanomedicine design, emphasis is centered on the engineered impacts of the nanomaterials (NMs). However, failure to understand the unintended effects of nanomaterials on the cell biology can affect the overall performance, approval, and adoption in the clinic. Much of these unintended effects arise from unique physico‐chemical properties of the NMs. This feature article discusses some of the key physico‐chemical parameters of NMs and highlights how they could cause unexpected and novel biological responses, with some insights into their underlying mechanisms.