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Growth of a Highly Porous Coordination Polymer on a Macroporous Polymer Monolith Support for Enhanced Immobilized Metal Ion Affinity Chromatographic Enrichment of Phosphopeptides
Author(s) -
Saeed Adeela,
Maya Fernando,
Xiao Dianne J.,
NajamulHaq Muhammad,
Svec Frantisek,
Britt David K.
Publication year - 2014
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201400116
Subject(s) - materials science , polymer , divinylbenzene , polystyrene , metal organic framework , porosity , monolith , chemical engineering , microporous material , chromatography , copolymer , organic chemistry , adsorption , styrene , catalysis , chemistry , composite material , engineering
A simple room temperature solution‐based method for the preparation of highly porous iron(III) benzenetricarboxylate coordination polymer films on the internal surface of a macroporous polystyrene‐divinylbenzene‐methacrylic acid polymer is reported. The resulting metal‐organic polymer hybrid (MOPH) maintains a high specific micropore surface area of 389 m 2 g ‐1 and thermal stability above 250 °C in air. The MOPH preparation is readily adapted to a capillary column, yielding a flow‐through separation device with excellent flow permeability and modest back‐pressure. The excellent separation capability of the MOPH column is demonstrated by enriching phosphopeptides from mixtures of digested proteins. This approach to MOPH synthesis is easily implemented and likely adaptable to a wide range of coordination polymers and metal‐organic frameworks.