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Biomimetics: Virus‐Tethered Magnetic Gold Microspheres with Biomimetic Architectures for Enhanced Immunoassays (Adv. Funct. Mater. 12/2013)
Author(s) -
Jeon Chang Su,
Hwang Inseong,
Chung Taek Dong
Publication year - 2013
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201370059
Subject(s) - materials science , microsphere , nanotechnology , colloidal gold , immunoassay , surface modification , scaffold , biomimetics , nanoparticle , chemical engineering , biomedical engineering , antibody , engineering , immunology , biology , medicine
Inspired by the cellular threadlike structures, virus‐decorated gold microspheres with high surface to volume ratios are described by Chang Su Jeon, Inseong Hwang, and Taek Dong Chung on page 1484 . The filamentous viral scaffold allows dense modification with antibodies, while the thin gold layer protects non‐specific bindings from serum samples, resulting in a significant increase in sensitivity in the bead‐based immunoassay.