Premium
Cell Separation: Ethanol‐Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4 + T Lymphocytes (Adv. Funct. Mater. 21/2012)
Author(s) -
Jun SeungHyun,
Kim Kwanghee,
An Hyo Jin,
Kim Byoung Chan,
Sonn Chung Hee,
Kim Miju,
Doh Junsang,
Yee Cassian,
Lee KyungMi,
Kim Jungbae
Publication year - 2012
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201290125
Subject(s) - materials science , nanofiber , electrospinning , polystyrene , maleic anhydride , conjugated system , immune system , nanotechnology , polymer , copolymer , immunology , biology , composite material
Electrospun and alcohol‐dispersed polystyrene‐poly(styreneco‐maleic anhydride) (PS‐PSMA) nanofibers, which allow for facile conjugation of antibodies, are used as an innovative cell isolation/enrichment and support/release platform. As reported by Kyung‐Mi Lee, Jungbae Kim, and co‐workers on page 4448 , this work opens up the potential for an innovative immune cell therapy in which specific immune cells are isolated by antibody‐conjugated nanofibers and are directly delivered to the target sites under the controlled and sustained release of immune cells via in vivo activation.