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Drug Delivery: Design and Synthesis of Multifunctional Drug Carriers Based on Luminescent Rattle‐Type Mesoporous Silica Microspheres with a Thermosensitive Hydrogel as a Controlled Switch (Adv. Funct. Mater. 7/2012)
Author(s) -
Kang Xiaojiao,
Cheng Ziyong,
Yang Dongmei,
Ma Ping'an,
Shang Mengmeng,
Peng Chong,
Dai Yunlu,
Lin Jun
Publication year - 2012
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201290042
Subject(s) - materials science , mesoporous silica , mesoporous material , nanotechnology , microsphere , luminescence , drug delivery , controlled release , optoelectronics , chemical engineering , organic chemistry , chemistry , engineering , catalysis
Multifunctional rattle‐type microspheres integrating the advantages of being mesoporous, luminescent, and temperature responsive into one single entity are fabricated. As reported by Ziyong Cheng, Jun Lin, and co‐workers on page 1470 , the composite shows red emission and can potentially be applied as a spin‐lattice relaxation time (T 1 )‐positive contrast agent due to the Gd 2 O 3 :Eu 3+ core. The rate of drug release can be regulated via a change in temperature due to controlled switching of the hydrogel.