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Drug Delivery: Harnessing Interfacial Phenomena to Program the Release Properties of Hollow Microcapsules (Adv. Funct. Mater. 1/2012)
Author(s) -
Lee Myung Han,
Hribar Kolin C.,
Brugarolas Teresa,
Kamat Neha P.,
Burdick Jason A.,
Lee Daeyeon
Publication year - 2012
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201290001
Subject(s) - materials science , plga , dispersity , template , drug delivery , chemical engineering , nanotechnology , glycolic acid , lactic acid , nanoparticle , polymer chemistry , biology , bacteria , engineering , genetics
The generation of near‐infrared‐sensitive microcapsules with programmable release properties is reported by Daeyeon Lee and co‐workers on page 131 . Poly(DL‐lactic‐ co ‐glycolic) acid (PLGA) microcapsules are generated using monodisperse water‐in‐oil‐inwater double emulsions as templates. The composition of the oil phase of double emulsions and that of PLGA determine the morphology and, in turn, the release properties of microcapsules. These microcapsules enable the release of hydrophobic and hydrophilic agents in a programmed sequence.