Biomimetic Membrane System Composed of a Composite Interpenetrating Hydrogel Film and a Lipid Bilayer | Zendy

Stidder Barry | Zendy; Alcaraz JeanPierre | Zendy; Liguori Lavinia | Zendy; Khalef Nawel | Zendy; Bakri Aziz | Zendy; Watkins Erik B. | Zendy; Cinquin Philippe | Zendy; Martin Donald K. | Zendy

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Biomimetic Membrane System Composed of a Composite Interpenetrating Hydrogel Film and a Lipid Bilayer

Author(s) -

Stidder Barry,

Alcaraz JeanPierre,

Liguori Lavinia,

Khalef Nawel,

Bakri Aziz,

Watkins Erik B.,

Cinquin Philippe,

Martin Donald K.

Publication year - 2012

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201200751

Subject(s) - materials science , polyelectrolyte , membrane , bilayer , lipid bilayer , adsorption , chemical engineering , diffusion , polyelectrolyte adsorption , agarose , nanotechnology , polymer , composite material , chromatography , organic chemistry , chemistry , biochemistry , physics , engineering , thermodynamics

A simple way to form an interpenetrating hydrogel (IPH) by combining a layer‐by‐layer polyelectrolyte membrane with agarose is reported. The formed IPH membrane is more robust and easily manipulated compared to a polyelectrolyte membrane with the same number of layers. The IPH has good diffusion characteristics and retains the advantageous surface charge from the polyectrolyte composition that facilitates the adsorption of a stable lipid bilayer. The stable adsorption of a lipid bilayer on the IPH creates a biomimetic membrane system that is optimized for utilization in a diffusion chamber.

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