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Cell‐Exclusion Patterning: Rehydration of Polymeric, Aqueous, Biphasic System Facilitates High Throughput Cell Exclusion Patterning for Cell Migration Studies (Adv. Funct. Mater. 15/2011)
Author(s) -
Tavana Hossein,
Kaylan Kerim,
BersanoBegey Tommaso,
Luker Kathryn E.,
Luker Gary D.,
Takayama Shuichi
Publication year - 2011
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201190062
Subject(s) - materials science , monolayer , cell , throughput , cell migration , aqueous solution , nanotechnology , biophysics , chemistry , biology , biochemistry , computer science , organic chemistry , telecommunications , wireless
A new cell‐exclusion patterning technique is presented by Shuichi Takayama and co‐workers on page 2920 . Rehydration of dried polymeric aqueous two‐phase systems results in well‐defined cell‐excluded circular gaps within a cell monolayer to serve as a migration niche for cells. The utility of this approach is demonstrated for high‐throughput quantitative cancer‐cell migration studies.