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Magnetic Molecularly Imprinted Polymer Nanocomposites via Surface‐Initiated RAFT Polymerization
Author(s) -
Gonzato Carlo,
Courty Matthieu,
Pasetto Pamela,
Haupt Karsten
Publication year - 2011
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201100466
Subject(s) - raft , materials science , superparamagnetism , molecularly imprinted polymer , polymer , chemical engineering , polymerization , methacrylate , ethylene glycol , nanoparticle , molecular imprinting , reversible addition−fragmentation chain transfer polymerization , surface modification , nanocomposite , polymer chemistry , nanotechnology , radical polymerization , chemistry , organic chemistry , composite material , selectivity , catalysis , physics , magnetization , quantum mechanics , magnetic field , engineering
Abstract A general protocol to synthesize superparamagnetic molecularly imprinted polymer particles, using a RAFT‐mediated approach, is described. S‐ propranolol‐imprinted composites were obtained by functionalizing commercially available amino‐modified Fe 3 O 4 nanoparticles with a trithiocarbonate agent and subsequently by polymerizing thin molecularly imprinted layers. Different parameters were optimized and their effect on both nanomorphology and imprinting behaviour was studied. Optimum conditions allowed the synthesis of 40 nm composite particles with a 7 nm MIP shell, exhibiting superparamagnetic properties and specific molecular recognition of S‐ propranolol. The possibility of fine‐tuning the surface properties of the particles is demonstrated by using the “living” nature of active RAFT fragments present on the surface of the composites to further functionalize the particles with ethylene glycol methacrylate phosphate polymer brushes.