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Magnetic/Silica Nanocomposites as Dual‐Mode Contrast Agents for Combined Magnetic Resonance Imaging and Ultrasonography
Author(s) -
Malvindi Maria Ada,
Greco Antonio,
Conversano Francesco,
Figuerola Albert,
Corti Maurizio,
Bonora Marco,
Lascialfari Alessandro,
Doumari Houshang Amiri,
Moscardini Marco,
Cingolani Roberto,
Gigli Giuseppe,
Casciaro Sergio,
Pellegrino Teresa,
Ragusa Andrea
Publication year - 2011
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201100031
Subject(s) - materials science , nanocomposite , magnetic resonance imaging , superparamagnetism , iron oxide , dual mode , nanoparticle , nanotechnology , nuclear magnetic resonance , iron oxide nanoparticles , ultrasonography , magnetic nanoparticles , nanocrystal , contrast (vision) , oxide , ultrasound , biomedical engineering , magnetic field , magnetization , radiology , optics , medicine , metallurgy , physics , quantum mechanics , aerospace engineering , engineering
A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt‐iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual‐mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US).