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Electrochemically Stimulated Release from Liposomes Embedded in a Polyelectrolyte Multilayer
Author(s) -
Graf Norma,
Albertini Francesco,
Petit Tristan,
Reimhult Erik,
Vörös Janos,
Zambelli Tomaso
Publication year - 2011
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201002283
Subject(s) - polyelectrolyte , materials science , indium tin oxide , vesicle , layer (electronics) , chemical engineering , electrode , liposome , layer by layer , nanotechnology , membrane , polymer , composite material , chemistry , biochemistry , engineering
Triggered release of an entrapped dye from vesicles embedded in a polyelectrolyte multilayer (PEM), as a consequence of the electrochemically induced local pH change in the vicinity of the electrode, is reported. The PEM was deposited on an indium tin oxide (ITO) electrode wherein lipid vesicles filled with a fluorescent dye were embedded. The use of vesicles with a strong negative charge and the polyelectrolyte species of the PEM matrix with a polycation as topmost layer enabled the generation of a stable layer of liposomes in the PEM.