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Tissue Repair: Wet‐Spun Biodegradable Fibers on Conducting Platforms: Novel Architectures for Muscle Regeneration (Adv. Funct. Mater. 21/2009)
Author(s) -
Razal Joselito M.,
Kita Magdalena,
Quigley Anita F.,
Kennedy Elizabeth,
Moulton Simon E.,
Kapsa Robert M. I.,
Clark Graeme M.,
Wallace Gordon G.
Publication year - 2009
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.200990094
Subject(s) - materials science , ex vivo , regeneration (biology) , in vivo , nanotechnology , skeletal muscle , biomedical engineering , substrate (aquarium) , tissue engineering , muscle tissue , anatomy , microbiology and biotechnology , biology , medicine , ecology
Bio‐synthetic platforms, consisting of a conducting polymer substrate overlaid with aligned biodegradable fibers promote the linear growth (ex vivo) of partially differentiated muscle fibers, consistent with the structural requirements of skeletal muscle in vivo, as described by J. M. Razal et al. on page 3381 . The conducting surface facilitates development of electrical stimulation paradigms for optimizing muscle growth and development ex vivo that may potentially be applied to repair diseased or damaged muscle.