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Fluorescent Nanoprobes: Fluorescent Gold Nanoprobe Sensitive to Intracellular Reactive Oxygen Species (Adv. Funct. Mater. 12/2009)
Author(s) -
Lee Hyukjin,
Lee Kyuri,
Kim InKyung,
Park Tae Gwan
Publication year - 2009
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.200990049
Subject(s) - nanoprobe , colloidal gold , fluorescence , materials science , intracellular , reactive oxygen species , biophysics , nanoparticle , nanotechnology , fluorescein , chemistry , biochemistry , biology , physics , quantum mechanics
On page 1884 , H. Lee and co‐workers report fluorescent gold nanoprobes sensitive to reactive oxygen species (ROS). Using nanoparticle surface energy transfer between gold nanoparticles and end‐dopamine modified fluorescein‐hyaluronic acid conjugates, gold nanoprobes are created with extreme sensitivity to intracellular ROS. The cover image shows real time monitoring of intracellular ROS generation within macrophage cells via fluorescence recovery of the nanoprobes.