Premium
DNA Detection: Intercalating Dye Harnessed Cationic Conjugated Polymer for Real‐Time Naked‐Eye Recognition of Double‐Stranded DNA in Serum (Adv. Funct. Mater. 9/2009)
Author(s) -
Pu KanYi,
Liu Bin
Publication year - 2009
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.200990032
Subject(s) - cationic polymerization , intercalation (chemistry) , conjugated system , dna , fluorescence , naked eye , materials science , polymer , double stranded , photochemistry , nanotechnology , biophysics , polymer chemistry , optics , organic chemistry , chemistry , biochemistry , biology , physics , composite material
On page 1371 , Liu Bin and Pu Kan‐Yi demonstrate multicolor detection of double‐stranded DNA in biological media using an intercalating‐dye‐harnessed cationic conjugated polymer. As demonstrated in the cover image, the intercalating‐dye‐harnessed polymer emits blue fluorescence both in the absence and presence of single‐stranded DNA in serum‐containing solution, while its fluorescence gradually turns from blue to dark yellow with increasing double‐stranded DNA concentration.