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Biological Sensor Platforms: Photoluminescence Detection of Biomolecules by Antibody‐Functionalized Diatom Biosilica (Adv. Funct. Mater. 6/2009)
Author(s) -
Gale Debra K.,
Gutu Timothy,
Jiao Jun,
Chang ChihHung,
Rorrer Gregory L.
Publication year - 2009
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.200990019
Subject(s) - biomolecule , materials science , photoluminescence , diatom , biosensor , surface modification , nanotechnology , nanoscopic scale , colloidal gold , nanoparticle , chemical engineering , optoelectronics , biology , botany , engineering
Microscopic shells of single‐celled algae called diatoms possess intricate nanoscale features composed of photoluminescent biosilica. On page 926 , the functionalization of the 10 µm centric diatom Cyclotella (center image) with the antibody Immunoglobulin G, and its use as a biosensor for immunocomplex formation are reported by D. K. Gale et al. Such formation is visible across the entire biosilica surface using FITC‐labeled antigen (green image) and antigen labeled with 10 nm gold nanoparticles (top image).