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Stereoselective and Enantioselective Electrochemical Sensing of Monosaccharides Using Imprinted Boronic Acid‐Functionalized Polyphenol Films
Author(s) -
Granot Eran,
TelVered Ran,
Lioubashevski Oleg,
Willner Itamar
Publication year - 2008
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.200700498
Subject(s) - monosaccharide , boronic acid , mannose , redox , ferrocene , electrochemistry , materials science , polymer , organic chemistry , combinatorial chemistry , chemistry , electrode
Imprinted polymer films for the selective analysis of D‐glucose and D‐mannose are prepared by the co‐electropolymerization of phenol with a 3‐hydroxyphenyl boronic acid‐monosaccharide complex containing D‐glucose or D‐mannose on a Au support. The analysis of the monosaccharides is based on a competitive electrochemical assay that employs the ferrocene‐modified‐monosaccharides as the redox labels. Similarly, enantioselectivity is demonstrated by the imprint of D‐glucose recognition sites in the polymer and the application of the redox‐active indicator.