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Superparamagnetic Manganese Ferrite and Strontium Bioactive Glass Nanocomposites: Enhanced Biocompatibility and Antimicrobial Properties for Hyperthermia Application
Author(s) -
Tripathi Himanshu,
Pandey Gaurav Chandra,
Dubey Ashutosh,
Shaw Subham Kumar,
Prasad Nand Kishore,
Singh S. P.,
Rath Chandana
Publication year - 2021
Publication title -
advanced engineering materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 114
eISSN - 1527-2648
pISSN - 1438-1656
DOI - 10.1002/adem.202000275
Subject(s) - materials science , biocompatibility , superparamagnetism , simulated body fluid , nanocomposite , scanning electron microscope , composite material , fourier transform infrared spectroscopy , ferrite (magnet) , bioactive glass , diffractometer , strontium , chemical engineering , metallurgy , organic chemistry , chemistry , quantum mechanics , magnetic field , physics , magnetization , engineering
Herein, the strontium bioactive glass with ferrite composites is studied for the application of biocompatibility and magnetic hyperthermia. The bioactive glass SrBG (46.1SiO 2 –21.9CaO–24.4Na 2 O–2.6P 2 O 5 –5SrO) prepared by the melt quench technique at 1400 °C and manganese ferrite (MnFe 2 O 4 ) prepared by the modified microwave reflux oven are mixed together and sintered at 400 °C for 6 h for making composites. The in vitro bioactivity of these composites is observed by immersing in simulated body fluid (SBF). The growth of the precipitated hydroxyapatite phase observed after SBF treatment is confirmed by the X‐ray diffractometer (XRD), Fourier transform infrared (FTIR) spectrometer, and scanning electron microscope (SEM) results. The in vitro cell viability assessment of these composites with MG‐63 cell lines indicates that the composites are biocompatible in nature. Furthermore, these composites show the antibacterial effect on the E. coli and S. Aureus bacteria cells. The room temperature superparamagnetic behavior accompanied by the heating ability in these composites proves their potential role for hyperthermia applications.