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Effects of Superimposed Micro/Nano‐Structured Titanium Alloy Surface on Cellular Behaviors In Vitro
Author(s) -
Wang Teng,
Wan Yi,
Liu Zhanqiang
Publication year - 2016
Publication title -
advanced engineering materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 114
eISSN - 1527-2648
pISSN - 1438-1656
DOI - 10.1002/adem.201600045
Subject(s) - biocompatibility , materials science , nano , titanium , titanium alloy , alloy , adhesion , nanotechnology , hydrothermal circulation , surface modification , metallurgy , chemical engineering , composite material , engineering
Surface modification has been widely applied in biomedical fields to improve the bioactivity and biocompatibility of biomedical implants. In this research, a novel superimposed micro/nano‐structured titanium alloy surface is obtained by hybrid micro‐milling technology and alkali‐hydrothermal reaction. The results indicate that substrates with micro/nano‐structure provide a beneficial interfacial environment for the growth of MC3T3s. The cell adhesion and proliferation are improved with alkali‐hydrothermal reaction. Furthermore, the superimposed micro/nano‐structured surface is conducive to induce the differentiation of MC3T3s. Conclusions demonstrate that micro/nano‐structured surface is a promising method for improving the biocompatibility of titanium alloy implants.