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Bioactive and Degradable Composite Microparticulates for the Tissue Cell Population and Osteogenic Development
Author(s) -
Yu HyeSun,
Hong SeokJung,
Park JeongHui,
Jeong Ishik,
Kim HaeWon
Publication year - 2009
Publication title -
advanced engineering materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 114
eISSN - 1527-2648
pISSN - 1438-1656
DOI - 10.1002/adem.200900106
Subject(s) - composite number , materials science , regeneration (biology) , biomedical engineering , population , biopolymer , staining , microsphere , cell , substrate (aquarium) , tissue engineering , microbiology and biotechnology , biophysics , nanotechnology , chemical engineering , chemistry , pathology , biology , biochemistry , composite material , medicine , polymer , ecology , environmental health , engineering
Bioactive and degradable composite microspheres (bioactive glass–synthetic biopolymer) were produced to deliver tissue cells and to aid their osteogenic development targeted for hard tissues. Cellular population (left, SEM cell image at day 3) and osteoblastic differentiation (right, immunofluorescence staining with bone marker at day 14) on the microspheres was evident, suggesting the composite microspheres provided effective 3D substrate conditions for hard tissue regeneration.