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Therapy with Cell Encapsulation for Substitution of Organ Function and Tumor Treatment
Author(s) -
Löhr J. Matthias,
Heuchel Rainer,
Jesnowski Ralf,
Wallrapp Christine
Publication year - 2009
Publication title -
advanced engineering materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 114
eISSN - 1527-2648
pISSN - 1438-1656
DOI - 10.1002/adem.200800409
Subject(s) - prodrug , cell encapsulation , materials science , encapsulation (networking) , pharmacology , drug , cancer research , cell , nanotechnology , medicine , biochemistry , chemistry , computer science , computer network
Cell encapsulation represents an innovative technique. However, clinical applications are sparse. Most experiments and clinical studies have been performed with either alginate or cellulose sulfate capsules, containing several cell lines and a broad variety of applications, ranging all the way from substitution for impaired organ function and release of cytokines or growth factors to gene‐directed enzyme prodrug therapy. A few clinical studies have been conducted and/or are under way.