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A Novel Biomimetic Hybrid Material Made of Silicified Collagen: Perspectives for Bone Replacement
Author(s) -
Heinemann S.,
Heinemann C.,
Ehrlich H.,
Meyer M.,
Baltzer H.,
Worch H.,
Hanke T.
Publication year - 2007
Publication title -
advanced engineering materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 114
eISSN - 1527-2648
pISSN - 1438-1656
DOI - 10.1002/adem.200700219
Subject(s) - materials science , biomimetic materials , polymer science , nanotechnology , composite material
Recent findings have generated new interest in the biomaterial properties of silica‐containing structures useful for bone replacement. The sol‐gel‐route seems to be most appropriate to mimic biological processing because it works under ambient conditions and furthermore allows the formation of a mineral phase from solution and the integration of a second component. The present work provides a strategy to mimic the natural processes of biosilicification under ambient conditions. By going beyond the nano‐ and micro‐level, the authors established an advanced procedure for the preparation of monolithic silica‐collagen hybrid xerogels.