Open AccessCell‐Derived Vesicles: Cell‐Derived Vesicles as TRPC1 Channel Delivery Systems for the Recovery of Cellular Respiratory and Proliferative Capacities (Adv. Biosys. 11/2020)
Author(s) -
Kurth Felix,
Tai Yee Kit,
Parate Dinesh,
Oostrum Marc,
Schmid Yannick R. F.,
Toh Shi Jie,
Yap Jasmine Lye Yee,
Wollscheid Bernd,
Othman Alaa,
Dittrich Petra S.,
FrancoObregón Alfredo
Publication year - 2020
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.202070111
Subject(s) - vesicle , microbiology and biotechnology , trpc1 , mitochondrion , cell , chemistry , biology , biophysics , biochemistry , ion channel , receptor , membrane
Mitochondrial function is central to human health and has been recently shown to be modulated by magnetic field‐induced TRPC1 (red) activation. In article number 2000146, Petra S. Dittrich, Alfredo Franco‐Obregón, and co‐workers show that cell‐derived vesicles from wild type muscle are capable of reinstating lost mitochondrial sensitivity to magnetic fields in muscle cells in which TRPC1 had been genetically silenced.