Open AccessPolyalkoxyvanadates: Insulin‐Sensitizing Activity of Sub‐Nanoscaled Polyalkoxyvanadate Clusters (Adv. Biosys. 5/2020)
Author(s) -
Chen Kun,
Jia Hongli,
Liu Yuan,
Yin Panchao,
Wei Yongge
Publication year - 2020
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.202070051
Subject(s) - insulin , myristic acid , pancreas , chemistry , medicine , pharmacology , materials science , biochemistry , fatty acid , palmitic acid
In article number 1900281, Panchao Yin, Yongge Wei, and co‐workers show that sub‐nanoscaled polyalkoxyvanadates (PAOVs) functionalized with aliphatic acids can restore the blood glucose to normal levels after a single oral administration. Among them, myristic acid‐modified PAOV derivatives sensitize the responsiveness of insulin to almost match that of a healthy pancreas.