Open AccessCell Stretching: Stretching Induces Overexpression of RhoA and Rac1 GTPases in Breast Cancer Cells (Adv. Biosys. 2/2020)
Author(s) -
Yadav Sharda,
Barton Matthew,
Nguyen NamTrung
Publication year - 2020
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.202070022
Subject(s) - rhoa , rac1 , gtpase , cancer cell , cancer , cancer research , breast cancer , small gtpase , cell , microbiology and biotechnology , chemistry , medicine , biology , signal transduction , biochemistry
In article number 1900222, Nam‐Trung Nguyen, Sharda Yadav, and Matthew Barton report a new stretching strategy to overexpress the protein markers of the Rho family in cancer cells. The levels of markers such as RhoA and Rac1 increase significantly after stretching cancer cells when compared to control cells. Cancer biomarkers expression is enhanced by stretching. Stretching cells may allow for overexpression and early diagnosis of cancer.