Open AccessIn Vivo Toxicity: In Vivo Toxicity Assessment of Hybrid Diatomite Nanovectors Using Hydra vulgaris as a Model System (Adv. Biosys. 4/2019)
Author(s) -
Terracciano Monica,
Stefano Luca,
Tortiglione Claudia,
Tino Angela,
Rea Ilaria
Publication year - 2019
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.201970042
Subject(s) - lernaean hydra , in vivo , toxicity , chemistry , biology , microbiology and biotechnology , organic chemistry
Diatomite nanoparticles are considered a valid alternative to the synthetic porous silica ones for nano‐based drug delivery systems. In article number 1800247 , Luca De Stefano, Claudia Tortiglione, and co‐workers explore the in vivo toxicity of hybrid diatomite nanovectors (DNPs) in a living model organism, the cnidarian freshwater polyp Hydra . The long‐term effects of DNPs on Hydra , based on multiple toxicity endpoints (morphology, growth rate, apoptosis, genetic analysis), demonstrate the in vivo biosafety of this naturally derived material.