In Vivo Toxicity: In Vivo Toxicity Assessment of Hybrid Diatomite Nanovectors Using  Hydra vulgaris  as a Model System (Adv. Biosys. 4/2019) | Zendy

Terracciano Monica | Zendy; Stefano Luca | Zendy; Tortiglione Claudia | Zendy; Tino Angela | Zendy; Rea Ilaria | Zendy

Open Access

In Vivo Toxicity: In Vivo Toxicity Assessment of Hybrid Diatomite Nanovectors Using Hydra vulgaris as a Model System (Adv. Biosys. 4/2019)

Author(s) -

Terracciano Monica,

Stefano Luca,

Tortiglione Claudia,

Tino Angela,

Rea Ilaria

Publication year - 2019

Publication title -

advanced biosystems

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.153

H-Index - 18

ISSN - 2366-7478

DOI - 10.1002/adbi.201970042

Subject(s) - lernaean hydra , in vivo , toxicity , chemistry , biology , microbiology and biotechnology , organic chemistry

Diatomite nanoparticles are considered a valid alternative to the synthetic porous silica ones for nano‐based drug delivery systems. In article number 1800247 , Luca De Stefano, Claudia Tortiglione, and co‐workers explore the in vivo toxicity of hybrid diatomite nanovectors (DNPs) in a living model organism, the cnidarian freshwater polyp Hydra . The long‐term effects of DNPs on Hydra , based on multiple toxicity endpoints (morphology, growth rate, apoptosis, genetic analysis), demonstrate the in vivo biosafety of this naturally derived material.

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