Open AccessMatrix‐Embedded Cells: Matrix‐Embedded Endothelial Cells Attain a Progenitor‐Like Phenotype (Adv. Biosys. 9/2017)
Author(s) -
Abraham Eytan,
Gadish Or,
Franses Joseph W.,
Chitalia Vipul C.,
Artzi Natalie,
Edelman Elazer R.
Publication year - 2017
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.201770069
Subject(s) - progenitor cell , phenotype , matrix (chemical analysis) , microbiology and biotechnology , progenitor , viral matrix protein , endothelial stem cell , biology , in vivo , endothelial progenitor cell , chemistry , stem cell , in vitro , genetics , gene , chromatography
Natalie Artzi and co‐workers describe how matrix‐embedded endothelial cells (MEEC) attain a progenitor‐like phenotype as defined by comparisons of secretome, phenotype, and genetic fingerprint of MEECs with that of endothelial progenitor cells, in article number 1700057 . The cover shows MEECs (green) wrapping around the denatured collagen structure (red) of the matrix, recapitulating in vivo endothelial structure much more closely than endothelial cells grown on 2D surfaces.