Open AccessDrug Delivery: Extracellular Vesicle Production Loaded with Nanoparticles and Drugs in a Trade‐off between Loading, Yield and Purity: Towards a Personalized Drug Delivery System (Adv. Biosys. 5/2017)
Author(s) -
Piffoux Max,
Silva Amanda K. A.,
Lugagne JeanBaptiste,
Hersen Pascal,
Wilhelm Claire,
Gazeau Florence
Publication year - 2017
Publication title -
advanced biosystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.153
H-Index - 18
ISSN - 2366-7478
DOI - 10.1002/adbi.201770025
Subject(s) - drug delivery , drug , pharmacology , yield (engineering) , extracellular vesicles , extracellular vesicle , targeted drug delivery , nanotechnology , chemistry , materials science , medicine , microvesicles , biochemistry , microbiology and biotechnology , microrna , gene , metallurgy , biology
The human body possesses its own outperforming delivery device in extracellular vesicles that circulate in all body fluids and act as a farreaching intercellular communication pathway. Engineering extracellular vesicles with therapeutic and imaging agents opens up unprecedented perspectives with a new generation of personalized drug delivery systems. In article number 1700044 , Florence Gazeau, Amanda K. A. Silva, and co‐workers compare methods of production, engineering, and purification of extracellular vesicles that challenge the road towards clinical translation.