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Parents' preferences for drug treatments in juvenile idiopathic arthritis: A discrete choice experiment
Author(s) -
Burnett Heather F.,
Regier Dean A.,
Feldman Brian M.,
Miller Fiona A.,
Ungar Wendy J.
Publication year - 2012
Publication title -
arthritis care and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.032
H-Index - 163
eISSN - 2151-4658
pISSN - 2151-464X
DOI - 10.1002/acr.21698
Subject(s) - medicine , multinomial logistic regression , arthritis , juvenile , preference , disease , activities of daily living , discrete choice , physical therapy , clinical psychology , machine learning , biology , computer science , economics , genetics , microeconomics
Objective To examine parents' preferences for drug treatments and health outcomes in juvenile idiopathic arthritis (JIA) and identify demographic and health‐related factors that significantly impact choice. Methods A discrete choice experiment was conducted with 105 parents of children with JIA who were cared for by a rheumatologist at The Hospital for Sick Children in Canada. Attributes evaluated included “drug treatment,” “child reported pain from arthritis,” “participation in daily activities,” “side effects,” “days missed from school,” and “cost to you.” Multinomial logit regression was used to estimate the relative importance of each attribute level and interaction term. Results Parents made tradeoffs between characteristics of the drug treatments and health outcomes. “Participation in daily activities” was the most important attribute, followed by “child reported pain from arthritis” and “cost to you.” Parents of children with longer disease durations had stronger preferences for improved participation in daily activities, whereas parents of older JIA patients had stronger preferences for improved control of pain. Conclusion Parents of children with JIA demonstrated strong preferences for treatments that reduce pain and improve daily functioning regardless of the associated side effects, level of responsibility required for drug administration, and days missed from school. Parents of children with longer disease durations and those who had been prescribed aggressive therapies had a greater preference for treatment effectiveness. These findings support the need for considering parental preferences in decisions regarding the choice of treatment for JIA.