Open AccessDifferential impact of behavioral, social, and emotional apathy on Parkinson's disease
Author(s) -
Ang YuenSiang,
Lockwood Patricia L.,
Kienast Annika,
Plant Olivia,
Drew Daniel,
Slavkova Elitsa,
Tamm Marin,
Husain Masud
Publication year - 2018
Publication title -
annals of clinical and translational neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.824
H-Index - 42
ISSN - 2328-9503
DOI - 10.1002/acn3.626
Subject(s) - apathy , anhedonia , parkinson's disease , depression (economics) , medicine , disease , psychiatry , clinical psychology , affect (linguistics) , psychology , pathology , schizophrenia (object oriented programming) , communication , economics , macroeconomics
Apathy is highly prevalent in Parkinson's disease. New findings suggest the syndrome is multifaceted. Here, we investigate whether all aspects of apathy are equally affected in Parkinson's disease and whether different dimensions of apathy were associated with depression and anhedonia. On the Apathy Motivation Index, while behavioral apathy and social apathy were elevated, emotional motivation was relatively preserved in Parkinson's disease, although a few patients did show impaired emotional sensitivity. Behavioral and social, but not emotional, apathy was associated with depression and anhedonia. These findings suggest aspects of motivation can be selectively impaired in Parkinson's disease and may have implications for guiding treatment.