Open AccessSeroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
Author(s) -
Kim Ki Hoon,
Kim SuHyun,
Hyun JaeWon,
Kim Yeseul,
Park Hyewon,
Kim Ho Jin
Publication year - 2022
Publication title -
annals of clinical and translational neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.824
H-Index - 42
ISSN - 2328-9503
DOI - 10.1002/acn3.51642
Subject(s) - myelitis , medicine , seroprevalence , myelin oligodendrocyte glycoprotein , transverse myelitis , immunology , antibody , pathology , serology , multiple sclerosis , spinal cord , psychiatry , experimental autoimmune encephalomyelitis
Although myelitis is the second most common presentation in adults with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD), studies on MOG‐IgG seroprevalence in patients with myelitis episodes are sparse. Herein, we investigated MOG‐IgG seroprevalence in Korean adults who exhibited myelitis since 2017. Among 151 adults with acute myelitis, 11 (7.3%) tested positive for MOG‐IgG by the initial screening and 10 (6.6%) patients were finally diagnosed with MOGAD during the study period. This study is the first to provide data on MOG‐IgG seroprevalence in adults with myelitis and supports the clinical utility and importance of MOG‐IgG testing in myelitis episodes.