Open AccessProximal flow to middle cerebral artery is associated with higher thrombus density in terminal internal carotid artery occlusion
Author(s) -
Pikija Slaven,
Magdic Jozef,
KillerOberpfalzer Monika,
Florea Cristina,
Hauer Larissa,
Novak Helmut F.,
McCoy Mark R.,
Sellner Johann
Publication year - 2017
Publication title -
annals of clinical and translational neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.824
H-Index - 42
ISSN - 2328-9503
DOI - 10.1002/acn3.429
Subject(s) - medicine , middle cerebral artery , thrombus , occlusion , internal carotid artery , radiology , angiography , stroke (engine) , cardiology , hematocrit , cerebral angiography , common carotid artery , external carotid artery , carotid arteries , ischemia , mechanical engineering , engineering
Proximal collaterals may determine the composition of occluding thrombi in acute ischemic stroke ( AIS ) in addition to source, hematocrit, time, and medication. Here, we performed a retrospective study of 39 consecutive patients with radiological evidence of I‐, L‐, and T‐type terminal internal carotid artery occlusion. Middle cerebral artery ( MCA ) thrombus density was assessed on noncontrast enhanced CT and proximal collaterals on CT angiography. In patients with presence of proximal collaterals to the MCA we detected more hyperdense clots ( P = 0.003) and a higher frequency of leptomeningeal collaterals ( P = 0.008). We expand the spectrum of factors that potentially determine clot perviousness and evolution of ischemic stroke.