Open AccessFlattening filter free VMAT for a stereotactic, single‐dose of 30 Gy to lung lesion in a 15‐min treatment slot
Author(s) -
Pokhrel Damodar,
Sanford Lana,
Dhanireddy Bhaswanth,
Molloy Janelle,
Randall Marcus,
McGarry Ronald C.
Publication year - 2020
Publication title -
journal of applied clinical medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 48
ISSN - 1526-9914
DOI - 10.1002/acm2.12829
Subject(s) - medicine , nuclear medicine , radiosurgery , lung , radiology , stereotactic radiotherapy , radiation treatment planning , radiation therapy
Cone‐beam CT‐guided single dose of lung stereotactic body radiotherapy (SBRT) treatment with a flattening filter free (FFF) beam and volumetric modulated arc therapy (VMAT) is a safe and highly effective treatment modality for selective small lung lesions. Four‐dimensional (4D) CT‐based treatment plans were generated using advanced AcurosXB algorithm for heterogeneity corrections. 6X‐FFF beam produced highly conformal radiosurgical dose distribution to the target and reduced lung SBRT fraction duration to less than 10 min for a single dose of 30 Gy, significantly improving patient comfort and clinic workflow. Early follow‐up CT imaging results (mean, 8 months) show high local control rates (100%) with no acute lung or rib toxicity. Longer clinical follow‐up in a larger patient cohort managed in this fashion is underway to further validate this treatment approach.