Open AccessDNA methylation subtypes for ovarian cancer prognosis
Author(s) -
Yin Lili,
Zhang Ningning,
Yang Qing
Publication year - 2021
Publication title -
febs open bio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.718
H-Index - 31
ISSN - 2211-5463
DOI - 10.1002/2211-5463.13056
Subject(s) - ovarian cancer , oncology , dna methylation , cpg site , medicine , proportional hazards model , stage (stratigraphy) , biology , cancer , pathological , methylation , gene , genetics , paleontology , gene expression
Our analysis showed that ovarian cancer prognosis in patients with hypomethylation was significantly worse than in patients with hypermethylation. MET molecular subtypes can be used not only to evaluate ovarian cancer prognosis, but also to fully distinguish between the tumor stage and histological grade in patients with ovarian cancer.