Aquaporin 1 mediates early responses to osmotic stimuli in endothelial cells via the calmodulin pathway | Zendy

Jiang Yong | Zendy; Wang Chengqi | Zendy; Ma Rui | Zendy; Zhao Ying | Zendy; Ma Xinyue | Zendy; Wan Jiaxin | Zendy; Li Chunxiang | Zendy; Chen Fanghao | Zendy; Fang Fang | Zendy; Li Mingguang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Aquaporin 1 mediates early responses to osmotic stimuli in endothelial cells via the calmodulin pathway

Author(s) -

Jiang Yong,

Wang Chengqi,

Ma Rui,

Zhao Ying,

Ma Xinyue,

Wan Jiaxin,

Li Chunxiang,

Chen Fanghao,

Fang Fang,

Li Mingguang

Publication year - 2021

Publication title -

febs open bio

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.718

H-Index - 31

ISSN - 2211-5463

DOI - 10.1002/2211-5463.13020

Subject(s) - calmodulin , aquaporin , microbiology and biotechnology , osmotic shock , chemistry , biology , biochemistry , gene , enzyme

Upon exposure to osmotic stimuli, AQP1 is phosphorylated and translocates to the cell membrane. After the initial response, the Ca2+/CaMK2 pathway is activated to regulate membrane localization and the activity of AQP1, which leads to a change in cell size and adjustment to the environment. These changes are blocked by the calmodulin antagonist W‐7.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research