Open AccessExpression profiles and prognostic significance of AFTPH in different tumors
Author(s) -
Zhu Tengjiao,
Chen Yingtong,
Liu Zhongjun,
Leng Yuxin,
Tian Yun
Publication year - 2020
Publication title -
febs open bio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.718
H-Index - 31
ISSN - 2211-5463
DOI - 10.1002/2211-5463.13003
Subject(s) - cancer research , adenocarcinoma , cancer , medicine , biology , oncology
Aftiphilin (AFTPH) plays an important role in regulating intracellular trafficking, exocytosis, and pro‐inflammatory response. The potential role of AFTPH in cancers remains unclear. This study was the first to comprehensively analyze the expression profiles and prognostic role of AFTPH in solid tumors and hematological malignancies, as well as providing evidence for subsequent studies on the molecular mechanism governing this role. AFTPH was suggested to be a potential therapeutic target and prognostic biomarker for BRCA, DLBC, LUSC, and PAAD.