Open AccessAn investigation into the molecular basis of cancer comorbidities in coronavirus infection
Author(s) -
Facchiano Antonio,
Facchiano Francesco,
Facchiano Angelo
Publication year - 2020
Publication title -
febs open bio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.718
H-Index - 31
ISSN - 2211-5463
DOI - 10.1002/2211-5463.12984
Subject(s) - cancer , tmprss2 , medicine , transcriptome , diabetes mellitus , receptor , gene , coronavirus , oncology , comorbidity , kidney cancer , gene expression , bioinformatics , covid-19 , biology , endocrinology , genetics , disease , infectious disease (medical specialty)
Five receptors/interactors of coronaviruses may play a key role in COVID‐19 comorbidities. They are expressed in almost any body district and, regardless of coronavirus infection, are associated with several diseases, including those most frequently cooccurring in COVID‐19 patients. Their expression is strongly altered in many cancers and at least three of them may be relevant markers in kidney, liver and thyroid cancers.