Open AccessmiR‐642a‐5p partially mediates the effects of lipopolysaccharide on human pulmonary microvascular endothelial cells via eEF2
Author(s) -
Fei Liming,
Sun Gengyun,
You Qinghai
Publication year - 2020
Publication title -
febs open bio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.718
H-Index - 31
ISSN - 2211-5463
DOI - 10.1002/2211-5463.12969
Subject(s) - lipopolysaccharide , apoptosis , viability assay , ards , microrna , endothelial stem cell , immunology , western blot , microbiology and biotechnology , medicine , biology , lung , gene , biochemistry , in vitro
miR‐642a‐5p promotes lipopolysaccharide‐induced hyperpermeability and apoptosis by targeting eukaryotic elongation factor 2. Thus, miR‐642a‐5p and eukaryotic elongation factor 2 may be potential targets for acute lung injury/acute respiratory distress syndrome diagnosis or treatment.
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