Open AccessPre‐treatment with D942, a furancarboxylic acid derivative, increases desiccation tolerance in an anhydrobiotic tardigrade Hypsibius exemplaris
Author(s) -
Kondo Koyuki,
Mori Masaru,
Tomita Masaru,
Arakawa Kazuharu
Publication year - 2020
Publication title -
febs open bio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.718
H-Index - 31
ISSN - 2211-5463
DOI - 10.1002/2211-5463.12926
Subject(s) - cryptobiosis , desiccation tolerance , tardigrade , protein phosphatase 2 , ampk , biology , downregulation and upregulation , protein subunit , microbiology and biotechnology , protein kinase a , desiccation , activator (genetics) , biochemistry , proteome , kinase , chemistry , receptor , botany , gene , ecology
The tardigrade Hypsibius exemplaris has low tolerance to direct exposure to 50% relative humidity (RH) without preconditioning in a high RH environment. However, tardigrades pre‐treated with D942, a furancarboxylic acid derivative, partially acquired desiccation tolerance against 50% or even lower RH without preconditioning. Proteomic analysis of tardigrades treated with D942 indicated that responses to oxidative stress may be one of the underlying molecular mechanisms.