The role of aging in cancer | Zendy

Havas Aaron | Zendy; Yin Shanshan | Zendy; Adams P. D. | Zendy

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The role of aging in cancer

Author(s) -

Havas Aaron,

Yin Shanshan,

Adams P. D.

Publication year - 2022

Publication title -

molecular oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.332

H-Index - 88

eISSN - 1878-0261

pISSN - 1574-7891

DOI - 10.1002/1878-0261.13302

Subject(s) - proteostasis , telomere , epigenetics , biology , cellular senescence , senescence , telomerase , somatic cell , dna damage , cancer , genetics , dna methylation , bioinformatics , dna , gene , gene expression , phenotype

Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects including somatic mutations, proteostasis, mitochondria, metabolism, senescence, epigenetic regulation, immune regulation, DNA damage, and telomere function.

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