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Front Cover
Publication year - 2020
Publication title -
febs letters
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1002/1873-3468.13422
Subject(s) - heterotrimeric g protein , g protein coupled receptor , front cover , medicine , cover (algebra) , computer science , g protein , receptor , mechanical engineering , engineering
Cover illustration GPCRs and heterotrimeric G Proteins define the Hallmarks of Cancer. They act as cancer drivers by dysregulating oncocrine cellular signalling networks within and outside the tumor microenvironment. GPCR is schematized in pink, heterotrimeric G proteins in blue (Ga) and green (Gbg), the membrane in pale orange. Figure adapted from Hanahan and Weinberg, Cell, 2011 and modified from SMART (Servier Medical Art), licensed under a CC BY 3.0, and taken from “G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers” by N. Arang and J.S. Gutkind (pp. 4201–4232).