Front Cover

Cover illustration GPCRs and heterotrimeric G Proteins define the Hallmarks of Cancer. They act as cancer drivers by dysregulating oncocrine cellular signalling networks within and outside the tumor microenvironment. GPCR is schematized in pink, heterotrimeric G proteins in blue (Ga) and green (Gbg), the membrane in pale orange. Figure adapted from Hanahan and Weinberg, Cell, 2011 and modified from SMART (Servier Medical Art), licensed under a CC BY 3.0, and taken from “G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers” by N. Arang and J.S. Gutkind (pp. 4201–4232).