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Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
Author(s) -
Dory Magdalena,
Hatzimasoura Elizabeth,
Kállai Brigitta M.,
Nagy Szilvia K.,
Jäger Katalin,
Darula Zsuzsanna,
Nádai Tímea V.,
Mészáros Tamás,
LópezJuez Enrique,
Barnabás Beáta,
Palme Klaus,
Bögre László,
Ditengou Franck A.,
Dóczi Róbert
Publication year - 2018
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1002/1873-3468.12929
Subject(s) - phosphorylation , mapk/erk pathway , microbiology and biotechnology , auxin , kinase , protein kinase a , mitogen activated protein kinase , biology , chemistry , biochemistry , gene
Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase ( MAPK ) sites adjacent to the phosphorylation sites of the well‐characterised AGC kinase PINOID , which regulates the polar localisation of PIN s and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN 1 are phosphorylated in vitro by two environmentally activated MAPK s, MPK 4 and MPK 6. In contrast to AGC kinases, MAPK ‐mediated phosphorylation of PIN 1 at adjacent sites leads to a partial loss of the plasma membrane localisation of PIN 1. MAPK ‐mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.