Open AccessCyanohydrin Derivative of Sucrose via 3‐Ketosucrose
Author(s) -
Timme V.,
Buczys R.,
Buchholz K.
Publication year - 2002
Publication title -
engineering in life sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 57
eISSN - 1618-2863
pISSN - 1618-0240
DOI - 10.1002/1618-2863(20020806)2:8<225::aid-elsc225>3.0.co;2-p
Subject(s) - derivative (finance) , regioselectivity , substituent , hydrolysis , cyanohydrin , stereoselectivity , chemistry , sucrose , aqueous solution , protecting group , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , alkyl , financial economics , economics
The cyanohydrine of 3‐ketosucrose can be obtained in good yields and with high regioselectivity. The stereoselectivity is 90 % for the isomer with axial orientation of the cyano group. By this reaction route a sucrose derivative with CC bonding of the substituent can be obtained in two steps without protecting groups in aqueous media. By its hydrolysis 3‐cyanoglucose is accessible.