Open AccessOptimization of Biocatalysts for Technical Processes
Author(s) -
Pohl M.
Publication year - 2001
Publication title -
engineering in life sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 57
eISSN - 1618-2863
pISSN - 1618-0240
DOI - 10.1002/1618-2863(200107)1:1<17::aid-elsc17>3.0.co;2-q
Subject(s) - computer science , biochemical engineering , citation , a priori and a posteriori , engineering , world wide web , philosophy , epistemology
Biocatalysts (enzymes) receiving increased interest in the fine chemical industry do not all have the required properties a priori. While, conventionally, enzymes with appropriate properties have to be selected from the natural pool (microorganisms, plants and animals), natural enzymes can now be tailored by molecular biological methods. In the present study, the so‐called “rational protein design” method is shown to be effective in improving the stability and activity of two industrially important enzymes.