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Evaluation of gas chromatography coupled with low pressure plasma source mass spectrometry for the screening of volatile organic compounds in food
Author(s) -
O'Connor Gavin,
Rowland Steve J.,
Evans E. Hywel
Publication year - 2002
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/1615-9314(20020901)25:13<839::aid-jssc839>3.0.co;2-z
Subject(s) - chemistry , mass spectrometry , chromatography , gas chromatography , gas chromatography–mass spectrometry , volatile organic compound , detection limit , argon , analytical chemistry (journal) , helium , ion source , environmental chemistry , ion , organic chemistry
A number of ion sources, namely low pressure helium MIPs, and low pressure helium and argon ICPs, coupled to GC and mass spectrometry have been evaluated for the analysis of volatile organic compounds. The most promising of these was the argon LP‐ICP‐MS. Detection limits of between 7–206 pg monitoring m/z 35 for 35 Cl detection, and between 92–7800 pg monitoring m/z 13 for 13 C detection, were obtained for a range of chlorinated and unchlorinated organic compounds. The potential for determining empirical formulae was demonstrated by an excellent correlation between predicted and measured Cl/C ratios. The technique was successfully used for the headspace analysis of chlorinated and unchlorinated volatile and semi‐volatile compounds spiked into olive oil.