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Multivariate optimization of supported liquid membrane extraction of biogenic amines from wine samples prior to liquid chromatography determination as dabsyl derivatives
Author(s) -
Romero Roberto,
Jönsson Jan Åke,
Gázquez Domingo,
Bagur M. Gracia,
SánchezViñas Mercedes
Publication year - 2002
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/1615-9314(20020601)25:9<584::aid-jssc584>3.0.co;2-f
Subject(s) - extraction (chemistry) , chromatography , wine , phosphoric acid , fractional factorial design , factorial experiment , chemistry , amine gas treating , membrane , biogenic amine , central composite design , chemometrics , response surface methodology , organic chemistry , mathematics , biochemistry , receptor , food science , neurotransmitter , statistics
The application of the supported liquid membrane (SLM) technique for the extraction of biogenic amines is presented. For the extraction of these compounds, the SLM system has been applied, using di‐2‐ethylhexyl phosphoric acid as an anionic carrier incorporated into the membrane phase. The optimization of the extraction process, involving the composition of membrane liquid, is discussed. The simultaneous optimization of the extraction efficiencies of all the amines is achieved by a desirability function, using experimental design strategies (Doehlert's and full factorial designs). The proposed method is evaluated for the extraction of biogenic amines from wines by comparing the extraction efficiency values with those obtained for a composite amine standard solution. The results show no significant differences.