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Characterization of stationary phases by retention data and solvation parameters
Author(s) -
Rohrschneider Lutz
Publication year - 2001
Publication title -
journal of separation science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.72
H-Index - 102
eISSN - 1615-9314
pISSN - 1615-9306
DOI - 10.1002/1615-9314(20010101)24:1<3::aid-jssc3>3.0.co;2-o
Subject(s) - solvation , chemistry , characterization (materials science) , adsorption , polyethylene glycol , materials science , molecule , organic chemistry , nanotechnology
Method requirements for the characterization of stationary phases are established. The completeness of the method and the influence of a mixed retention mechanism involving both solvation and adsorption on characteristic phase parameters are discussed. The performance of the retention and the solvation parameter model for the characterization of stationary phases is compared. Stationary phases are characterized in the retention model by retention data measured for prototypical substances, and in the solvation parameter model by explanatory regression coefficients found by a statistical method. A new approach is proposed which combines the advantages of the retention and the solvation model. The low proton acidity of low molecular weight polyethylene glycol phases has been found with the combined model.