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Enantioselective Synthesis of the Molluscicidal Furanosesquiterpene Lactones Ricciocarpin A and Ricciocarpin B via Ring Closing Metathesis
Author(s) -
Held Christoph,
Fröhlich Roland,
Metz Peter
Publication year - 2002
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/1615-4169(200208)344:6/7<720::aid-adsc720>3.0.co;2-#
Subject(s) - chemistry , enantioselective synthesis , ring closing metathesis , metathesis , stereochemistry , ring (chemistry) , salt metathesis reaction , combinatorial chemistry , organic chemistry , catalysis , polymer , polymerization
Using two catalytic ring closing metatheses as the key events, a short, completely diastereoselective and highly enantioselective access to the molluscicidal sesquiterpenoids ricciocarpin A and ricciocarpin B was achieved. The hitherto unknown absolute configuration of these natural products is unambiguously established.